Dr. Richard Hare, a trainee at St. Swithin's Hospital in London, is a patient recuperating from jaundice. Love-prone, he falls for Sally Nightingale, his night nurse; and their indiscretion causes Sally to be dismissed. Upon his release from the hospital, Hare and his equally foolhardy colleague Dr. Tony Burke sign on as dollar-a-day guinea pigs at the Foulness Anti-Cold Research Unit, but a frolic with Leonora and Dawn, two uninhibited stripteasers, terminates that means of employment. Hare then becomes an assistant to Dr. Clive Cardew, a country physician married many times. Cardew goes to America to obtain his latest divorce, leaving Hare in charge of the clinic, and Hare invites Burke to join him in the country. Burke leaves, however, after a disastrous attempt to help Wildewinde, an oddball dispenser, take the drunkenness test at the local police station. Hare then hires as his assistant Dr. Nikki Barrington, also from St. Swithin's, with whom he promptly falls in love. All goes well until Sally Nightingale becomes the new receptionist, and Nikki, jealous of Hare's ex-lovers, walks out. A short time later they are both called to St. Swithin's to remove the appendix of Sir Lancelot Spratt, Hare's old superior; and the two lovers are reconciled at the operating table.